Pfizer Inc has launched their Portable Continuous Miniature and Modular (PCMM) autonomous manufacturing unit for continuous oral solid dose form production. The equipment fits in a portable facility that can be shipped to any location, enabling medicines to be manufactured where and when they are needed. The advantages of PCMM are significant:
Both PAT and Advanced Process Control are seamlessly embedded into the operator interface. PAT is used to generate predictions of Critical Quality Attributes. Model Predictive Control adjusts key process actuations in a co-ordinated manner, to minimise variability in final product quality and respond to changes in raw material quality.
This provides a fully-integrated environment for process monitoring, product quality assessment and process control.
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